• Only instrument that quantifies
the output of arterial baroreceptors
• Only off-the-shelf medical instrument for brainstem autonomic
function
•
The NeuroScope™ is now a text book method fore
the diagnosis of Rett Syndrome
Brainstem
dysfunctions in Rett syndrome
Episodes of
Abnormal Spontaneous Brainstem Activations (ASBA) are exaggerated
and simultaneous large increases in cardiac vagal tone, cardiac
sensitivity to baroreflex and arterial blood pressure in a
"Brainstem Storm". Feeble breathers who have
in addition a co-existing hypoxia and hypercapnoea (high level
of carbon dioxide in the blood) are predisposed to brainstem
storms. The large increases in cardiac vagal tone carry the
risk of cardiac arrest.
Julu, P.O.O
(2001). The central autonomic disturbance in Rett syndrome. In: Kerr,
A. and Witt Engerstrom, I (eds) Rett Disorder and the Developing
Brain. Oxford University Press, Oxford, pp132-181.
